BCC3805Lithocholic AcidLithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.(CAS NO.:434-13-9)
BCN5401ArenobufaginArenobufagin is a natural bufadienolide from toad venom; has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells.(CAS NO.:464-74-4)
BCN2358GamabufotalinGamabufotalin (Gamabufagin), a major bufadienolide of Chansu, has been used for cancer therapy due to its desirable metabolic stability and less adverse effect.(CAS NO.:465-11-2)
BCN5509NeritalosideBotanical source: The herbs of Nerium indicum Mill.(CAS NO.:465-13-4)
BCN5511OleandrinOleandrin inhibits the Na+, K+-ATPase activity with an IC50 of 620 nM. Oleandrin induces apoptosis via activating endoplasmic reticulum stress.(CAS NO.:465-16-7)
BCN1046BufalinBufalin is an active component isolated from Chan Su, acts as a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM, respectively. Anti-cancer activity.(CAS NO.:465-21-4)
BCN5366ResibufogeninResibufogenin, a component of huachansu, has been shown to exhibit the anti-proliferative effect against cancer cells, and this may be attributed to the degradation of cyclin D1 caused by the activation of GSK-3β.(CAS NO.:465-39-4)
BCN5510alpha-Spinasterol acetateBotanical source: The herbs of Inula britannica L.(CAS NO.:4651-46-1)
BCN5515UzarigeninBotanical source: The root of Calotropis gigantea(CAS NO.:466-09-1)
BCN5408HecogeninHecogenin is a steroid saponin isolated from Agave sisalana and is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of pharmacological activities, including anti-inflammatory, antifungal and gastroprotective effects.(CAS NO.:467-55-0)
BCN5367CinobufaginCinobufagin, a kind of Chinese materia medica with antitumor effect, is widely used in clinical practice, especially in anti-liver cancer.(CAS NO.:470-37-1)
BCC9238MarinobufaginMarinobufogenin is a strong inhibitor of Na+/K+ ATPase that has been identified in mammalian plasma.(CAS NO.:470-42-8)
BCN5368BufotalineBufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species; a novel anti-osteoblastoma agent.(CAS NO.:471-95-4)
BCN6287RuscogeninRuscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities.(CAS NO.:472-11-7)
BCN2359TelocinobufaginTelocinobufagin is one of anti-hepatoma constituent in Venenum Bufonis.(CAS NO.:472-26-4)
BCN2620Chenodeoxycholic acidChenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.(CAS NO.:474-25-9)
BCN7357CitrostadienolBotanical source: The herbs of Prunus armeniaca L.(CAS NO.:474-40-8)
BCN5531DaucosterolDaucosterol is a natural sterolin.(CAS NO.:474-58-8)
BCN3890CampestanolBotanical source: The seeds of Brassica campestris(CAS NO.:474-60-2)
BCN3181CampesterolCampesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.(CAS NO.:474-62-4)
BCN2613BrassicasterolBotanical source: The seeds of Brassica campestris L.(CAS NO.:474-67-9)
BCN5564alpha-Spinasterolα-Spinasterol, isolated from Spinacia oleracea, has antibacterial activity. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively.(CAS NO.:481-18-5)
BCN2203CorticosteroneCorticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.(CAS NO.:50-22-6)
BCN2192HydrocortisoneHydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.(CAS NO.:50-23-7)
