Iridin

CAS# 491-74-7

Iridin

Catalog No. BCN6868----Order now to get a substantial discount!

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Quality Control of Iridin

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Chemical structure

Iridin

3D structure

Chemical Properties of Iridin

Cas No. 491-74-7 SDF Download SDF
PubChem ID 5281777 Appearance White powder
Formula C24H26O13 M.Wt 522.46
Type of Compound Flavonoids Storage Desiccate at -20°C
Synonyms Irigenin 7-glucoside; 3',5,7-Trihydroxy 4',5',6-trimethoxyisoflavone 7-glucoside
Solubility Soluble in DMSO and methan
Chemical Name 5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
SMILES COC1=CC(=CC(=C1OC)O)C2=COC3=CC(=C(C(=C3C2=O)O)OC)OC4C(C(C(C(O4)CO)O)O)O
Standard InChIKey LNQCUTNLHUQZLR-OZJWLQQPSA-N
Standard InChI InChI=1S/C24H26O13/c1-32-13-5-9(4-11(26)22(13)33-2)10-8-35-12-6-14(23(34-3)19(29)16(12)17(10)27)36-24-21(31)20(30)18(28)15(7-25)37-24/h4-6,8,15,18,20-21,24-26,28-31H,7H2,1-3H3/t15-,18-,20+,21-,24-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Iridin

1 Iris sp. 2 Juniperus sp.

Protocol of Iridin

Kinase Assay

8-Hydroxyirilone 5-methyl ether and 8-hydroxyirilone, new antioxidant and α-amylase inhibitors isoflavonoids from Iris germanica rhizomes.[Pubmed: 28069265 ]

Bioorg Chem. 2017 Feb;70:192-198.

Iris species are well recognized as wealthy sources of isoflavonoids.
METHODS AND RESULTS:
In the present study, phytochemical investigation of the rhizomes of Iris germanica (Iridaceae) procure the isolation of two new isoflavonoids namely, 8-hydroxyirilone 5-methyl ether (2) and 8-hydroxyirilone (3), along with eight known isoflavonoids: irilone 4'-methyl ether (1), irilone (4), irisolidone (5), irigenin S (6), irigenin (7), irilone 4'-O-β-d-glucopyranoside (8), Iridin S (9), and Iridin (10). The isolated flavonoids were structurally characterized with the assist of comprehensive spectroscopic analyses (UV, IR, 1D and 2D NMR, and HRMS) and comparing with the published data. They were estimated for their antioxidant and antidaibetic capacities using DPPH and α-amylase inhibition assays, respectively.
CONCLUSIONS:
Compounds 2, 3, and 4 exhibited prominent antioxidant activities with IC50 values of 12.92, 9.23, and 10.46μM, respectively compared to propyl gallate (IC50 7.11μM). Moreover, 2-5 possessed highest α-amylase inhibitory activity with % inhibition 66.1, 78.3, 67.3, and 70.1, respectively in comparison to acarbose (reference α-amylase inhibitor). Additionally, their structure-activity relationship has been discussed.

Iridin Dilution Calculator

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Iridin Molarity Calculator

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Preparing Stock Solutions of Iridin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.914 mL 9.5701 mL 19.1402 mL 38.2804 mL 47.8506 mL
5 mM 0.3828 mL 1.914 mL 3.828 mL 7.6561 mL 9.5701 mL
10 mM 0.1914 mL 0.957 mL 1.914 mL 3.828 mL 4.7851 mL
50 mM 0.0383 mL 0.1914 mL 0.3828 mL 0.7656 mL 0.957 mL
100 mM 0.0191 mL 0.0957 mL 0.1914 mL 0.3828 mL 0.4785 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Iridin

8-Hydroxyirilone 5-methyl ether and 8-hydroxyirilone, new antioxidant and alpha-amylase inhibitors isoflavonoids from Iris germanica rhizomes.[Pubmed:28069265]

Bioorg Chem. 2017 Feb;70:192-198.

Iris species are well recognized as wealthy sources of isoflavonoids. In the present study, phytochemical investigation of the rhizomes of Iris germanica (Iridaceae) procure the isolation of two new isoflavonoids namely, 8-hydroxyirilone 5-methyl ether (2) and 8-hydroxyirilone (3), along with eight known isoflavonoids: irilone 4'-methyl ether (1), irilone (4), irisolidone (5), irigenin S (6), irigenin (7), irilone 4'-O-beta-d-glucopyranoside (8), Iridin S (9), and Iridin (10). The isolated flavonoids were structurally characterized with the assist of comprehensive spectroscopic analyses (UV, IR, 1D and 2D NMR, and HRMS) and comparing with the published data. They were estimated for their antioxidant and antidaibetic capacities using DPPH and alpha-amylase inhibition assays, respectively. Compounds 2, 3, and 4 exhibited prominent antioxidant activities with IC50 values of 12.92, 9.23, and 10.46muM, respectively compared to propyl gallate (IC50 7.11muM). Moreover, 2-5 possessed highest alpha-amylase inhibitory activity with % inhibition 66.1, 78.3, 67.3, and 70.1, respectively in comparison to acarbose (reference alpha-amylase inhibitor). Additionally, their structure-activity relationship has been discussed.

Description

Iridin is an isoflavone isolated from Iris milesii.

Keywords:

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