PPAR

The peroxisome proliferator-activated receptors (PPARs), belonging to the nuclear receptor superfamily, are a group of nuclear receptor proteins that are composed of three isoforms, including PPARγ, PPARα and PPARδ, encoded by separate genes. PPARs have a modular structure characterized by the presence of two highly conserved domains, including the DNA binding domain (DBD) of two zinc fingers and the ligand binding domain (LBD) of 13 α-helices and a small 4-stranded β-sheet. PPARs are ligand-regulated transcription factors controlling gene expression by binding to specific response elements (PPREs) within promoters, where PPARs bind as heterodimers with a retinoid X receptor and interact with cofactors upon binding leading to the increasing of rate of transcription initiation.

Products for PPAR

  1. Cat.No. Product Name Information
  2. BCC1337 AleglitazarPPARα/PPARγagonist
  3. BCC1395 BalaglitazonePPAR-γ partial agonist
  4. BCC1611 GW1929Potent PPARγ agonist
  5. BCC1652 InolitazonePPARgamma agonist
  6. BCC1653 Inolitazone dihydrochloridePPARγ agonist,high-affinity and novel
  7. BCC1687 L-165041PPARβ/δ agonist,cell permeable,potent and selective
  8. BCC2016 TroglitazoneSelective PPARγ agonist
  9. BCC2260 GW9662PPARγ antagonist
  10. BCC2261 T0070907Human PPARγ antagonist,potent and selective
  11. BCC2262 Rosiglitazone maleatePPARγ agonist,high-affinity and selective,potent insulin sensitizer
  12. BCC2263 GSK3787PPARβ/δ antagonist,novel and irreversible
  13. BCC2264 RosiglitazonePromotes differentiation of adipocytes; also potent and selective PPARγ agonist
  14. BCC2265 WY-14643 (Pirinixic Acid)PPARα agonist,selective and highly potent
  15. BCC2266 Ciprofibrate
  16. BCC2267 GW0742PPARδ/β agonist,potent and selective
  17. BCC2268 GW501516PPARβ agonist,selective and potent
  18. BCC2269 Rosiglitazone HCl
  19. BCC2278 Pioglitazone HClPPARγ agonist
  20. BCC4023 AUDA
  21. BCC4781 Fenofibrate
  22. BCC4783 Gemfibrozil
  23. BCC4927 Pioglitazone
  24. BCC5308 ClofibratePPAR agonist
  25. BCC6166 SR 1664
  26. BCC7014 Ciglitazone
  27. BCC7022 BADGE
  28. BCC7150 GW 7647
  29. BCC7243 SR 202PPAR antagonist
  30. BCC7268 nTZDpa
  31. BCC7321 15-deoxy-Δ-12,14-Prostaglandin J2
  32. BCC7688 GSK 0660
  33. BCC7751 S26948
  34. BCC7828 Tesaglitazar
  35. BCC7881 CP 775146

Items 1 to 34 of 34 total