Kalopanaxsaponin G

CAS# 57539-70-5

Kalopanaxsaponin G 2D chemical structure

2D Structure

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Chemical Properties of Kalopanaxsaponin G

Cas No. 57539-70-5 SDF File under preparation.
PubChem ID 171596.0 Appearance Powder
Formula C48H78O18 M.Wt 943.1
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
SMILES CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OCC3C(C(C(C(O3)OC(=O)C45CCC(CC4C6=CCC7C8(CCC(C(C8CCC7(C6(CC5)C)C)(C)CO)O)C)(C)C)O)O)O)CO)O)O)O
Standard InChIKey YGSBJLPWANWGED-HYXYOFMCSA-N
Standard InChI InChI=1S/C48H78O18/c1-22-30(52)32(54)35(57)40(62-22)65-38-25(19-49)63-39(37(59)34(38)56)61-20-26-31(53)33(55)36(58)41(64-26)66-42(60)48-16-14-43(2,3)18-24(48)23-8-9-28-44(4)12-11-29(51)45(5,21-50)27(44)10-13-47(28,7)46(23,6)15-17-48/h8,22,24-41,49-59H,9-21H2,1-7H3/t22-,24-,25+,26+,27+,28+,29-,30-,31+,32+,33-,34+,35+,36+,37+,38+,39+,40-,41-,44-,45-,46+,47+,48-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Quality Control of Kalopanaxsaponin G

3D structure

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Kalopanaxsaponin G

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Kalopanaxsaponin G Dilution Calculator

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Kalopanaxsaponin G Molarity Calculator

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Similar Structures

Preparing Stock Solutions of Kalopanaxsaponin G

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0603 mL 5.3017 mL 10.6033 mL 21.2067 mL 26.5083 mL
5 mM 0.2121 mL 1.0603 mL 2.1207 mL 4.2413 mL 5.3017 mL
10 mM 0.106 mL 0.5302 mL 1.0603 mL 2.1207 mL 2.6508 mL
50 mM 0.0212 mL 0.106 mL 0.2121 mL 0.4241 mL 0.5302 mL
100 mM 0.0106 mL 0.053 mL 0.106 mL 0.2121 mL 0.2651 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.
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References on Kalopanaxsaponin G

Separation of a new triterpenoid saponin together with six known ones from Clematis tangutica (Maxim.) Korsh and evaluation of their cytotoxic activities.[Pubmed:34587845]

Nat Prod Res. 2023 Feb;37(3):375-382.

A new triterpenoid saponin, 3-O-beta-D-allopyranosyl (1-->3)-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranosyl hederagenin 28-O-alpha-L-rhamnopyranosyl (1-->4)-beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl ester (IV), together with six known ones Hederacholichiside F (I), Tanguticoside B (II), Tauroside St-H(1) (III), Hederoside H(1) (V), Kalopanaxsaponin G (VI), Hederasaponin B (VII) were separated from Clematis tangutica (Maxim.) Korsh. Their cytotoxic activities were evaluated. Saponins IV (new compound) and I showed selective inhibitory activities against HGC-27 with IC(50) values of 20.17 and 66.18 muM. Saponin VII exhibited extensive inhibitory action against HGC-27, Hela and SK-OV-3 with IC(50) values of 16.47-71.36 muM. Saponin III showed selective inhibitory activity against SK-OV-3 with the IC(50) value of 48.70 muM. All isolated saponins were inactive (IC(50) >150 muM) to GES-1.

Triterpenoid saponins of Acanthopanax nipponicus leaves.[Pubmed:10096855]

J Nat Prod. 1999 Mar;62(3):445-8.

Five new triterpenoid saponins, nipponosides A-E (1, 3-6), were isolated from Acanthopanax nipponicus leaves, along with a known saponin, Kalopanaxsaponin G (2). Nipponosides A-E were characterized as the 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta -D-glucopyranosyl ester of 3-oxohederagenin, oleanolic acid 3-O-beta-D-glucopyranoside, gypsogenin 3-O-beta-D-glucopyranoside, 3beta,23,29-trihydroxyolean-12-en-28-oic acid, and 3beta,20alpha, 23-trihydroxy-30-nor-olean-12-en-28-oic acid, respectively. The structures of these new compounds were based on chemical and spectral methods.

Product Information

Kalopanaxsaponin G (CAS 57539-70-5) is a natural product offered by BioCrick for research applications. Customers can buy or order Kalopanaxsaponin G from BioCrick, a supplier and manufacturer of research chemicals, with product specifications, purity, packaging, and pricing information available upon request.

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