Estrogen/progestogen Receptor - Endocrinology and Hormones

Cat.No. Product Name Information

BCC7557 GSK 4716 GSK-4716 is a selective ERRβ/γ agonist.

BCC7701 FERb 033

BCC7761 Endoxifen Endoxifen Z-isomer is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα).

BCC6058 G-15 G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM. G-15

BCC5557 Ospemifene Ospemifene is a selective estrogen for the prevention of postmenopausal osteoporosis with IC50 values of 827nM and 1633nM for ERα and ERβ, respectively.

BCC1081 Fulvestrant Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and apoptosis and has antitumor efficacy.

BCC7224 (R,R)-THC

BCC6283 G-36 G-36

BCC7088 DPN DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor β(ER β) selective ligand. DPN

BCC7608 RU 58668

BCC1295 (Z)-2-decenoic acid (Z)-2-decenoic acid(cis-2-Decenoic acid) is an unsaturated short chain fatty acid that is secreted by P.

BCC7272 ZK 164015

BCC7831 Zearalenone Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts.

BCC4492 Bazedoxifene HCl Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively.

BCC1411 Bazedoxifene Bazedoxifene (TSE-424) is a selective estrogen receptor modulator (SERM) currently in development for osteoporosis prevention and treatment.

BCC1412 Bazedoxifene acetate Bazedoxifene acetate (TSE-424 acetate) is a third generation selective estrogen receptor modulator (SERM) with IC50s of 26 and 99 nM for ERα and ERβ, respectively.

BCC7839 Cyclofenil Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50

BCC7062 PPT Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). PPT

BCC4483 Ethynodiol diacetate Ethynodiol diacetate is a steroidal progestin which is used as a hormonal contraceptive, it has relatively little or no potency as an androgen,has significant estrogenic effects.

BCC4477 Estradiol Cypionate Estradiol cypionate is a 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptor IC50 value: Target: estrogen receptor Estradiol cypionate is a synthetic ester, is a estrogen.

BCC1292 (E)-2-Decenoic acid (E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.

BCC4478 Ethisterone Ethisterone is a progestogen hormone being considered to treat prostate cancer.

BCC7669 WAY 200070 WAY-200070 is a selective estrogen receptor β (ERRβ) agonist with an IC50 of 2.3 nM.

BCN2235 Estriol Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. Estriol

BCN2194 beta-Estradiol Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.

BCC4480 Clomiphene citrate Clomiphene citrate (Clomifene citrate) is a selective estrogen receptor modulator.

BCC7939 (R)-DPN (R)-DPN

BCC7903 ERB 041 Prinaberel(ERB-041) is a potent and selective ERbeta agonist; being >200-fold selective for ERbeta. ERB 041

BCN2201 Estrone Estrone is an estrogenic hormone. Estrone

BCN2855 4',7-Isoflavandiol (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.

BCC4491 Erteberel (LY500307) Erteberel (LY500307) is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively. Anti-tumor activities.

BCC5230 Etonogestrel Etonogestrel is a steroidal progestin used in hormonal contraceptives.

BCC4382 Tamoxifen Citrate Tamoxifen Citrate (ICI 46474) is a selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells.Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate activates autophagy and induces apoptosis.

BCC6442 Chlorotrianisene Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood.

BCC3777 Ethinyl Estradiol Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.

BCC7497 α-Estradiol Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

BCC4490 Gestodene Gestodene(SHB 331;WL 70) is a progestogen hormonal contraceptive.

BCC6015 (Z)-4-Hydroxytamoxifen 4-Hydroxytamoxifen is a selective estrogen receptor modulator (SERM).

BCC4485 Medroxyprogesterone acetate Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors。

BCC5121 XCT790 XCT-790 is a potent and selective inverse agonist for ERRα with an IC50 value of 0.37 μM. XCT-790 induces cell death in chemotherapeutic resistant cancer cells. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ. XCT790

BCC7719 Estropipate Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis.

BCC7447 PHTPP PHTPP is a selective ERβ antagonist. PHTPP

BCC4488 Raloxifene HCl Raloxifene hydrochloride (LY156758 hydrochloride; LY139481 hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue. Raloxifene HCl

BCC4484 Hexestrol Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.

BCC7451 Y 134 Y 134

BCC4479 Altrenogest Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone.

BCC6045 G-1 G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM. G-1

BCC2010 Toremifene Toremifene (NK 622; FC 1157a) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis.

BCC4487 Toremifene Citrate Toremifene Citrate(NK 622; FC 1157a) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis.

BCC7225 MPP dihydrochloride MPP dihydrochloride is a highly selective estrogen receptor alpha (ERα) antagonist. MPP dihydrochloride reduces the ratio of p-ERα/ERα.

Products for Estrogen/progestogen Receptor