Endocrinology and Hormones
The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.
Products for Endocrinology and Hormones
- GnRH(4)
- Estrogen/progestogen Receptor(50)
- Opioid Receptor(70)
- RAAS(7)
- Androgen Receptor(24)
- Aromatase(5)
- 5-alpha Reductase(3)
- Thyroid hormone Receptor(1)
- Non-selective AT(2)
- CRTH2(2)
- Cat.No. Product Name Information
- BCC1037 Angiotensin 1/2 + A (2 - 8)
- BCC4366 Spironolactone Spironolactone is a potent antagonist of the androgen receptor.
- BCC6368 Morphine hydrochloride
- BCN2748 Dimethylcurcumin Dimethylcurcumin (ASC-J9) is an androgen receptor degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion.
- BCC7939 (R)-DPN
- BCC7903 ERB 041 Prinaberel(ERB-041) is a potent and selective ERbeta agonist; being >200-fold selective for ERbeta.
- BCN2201 Estrone Estrone is an estrogenic hormone.
- BCN2855 4',7-Isoflavandiol (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.
- BCC5215 Buprenorphine hydrochloride
- BCC4491 Erteberel (LY500307) Erteberel (LY500307) is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively. Anti-tumor activities.
- BCC5230 Etonogestrel Etonogestrel is a steroidal progestin used in hormonal contraceptives.
- BCC4382 Tamoxifen Citrate Tamoxifen Citrate (ICI 46474) is a selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells.Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate activates autophagy and induces apoptosis.
- BCC6093 Nalmefene - d3
- BCC4369 Formestane Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
- BCC6442 Chlorotrianisene Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood.
- BCC3777 Ethinyl Estradiol Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.
- BCC7497 α-Estradiol Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
- BCC1035 Angiotensin 1/2 (1-5) Angiotensin I/II 1-5 is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
- BCC5831 [Leu5]-Enkephalin [Leu5]-Enkephalin is a pentapeptides with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
- BCC7857 Nalmefene hydrochloride
- BCC4920 Meptazinol HCl Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM.
- BCC4490 Gestodene Gestodene(SHB 331;WL 70) is a progestogen hormonal contraceptive.
- BCC1754 MK-0773 MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM.
- BCC2140 Captopril Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE).
- BCC1425 BMS-564929 BMS-564929 is an androgen receptor (AR) agonist, binds to androgen receptor (AR) with a Ki of 2.11±0.16 nM.
- BCC6064 DADLE
- BCC5352 Goserelin Acetate Goserelin(ICI 118630) is an injectable gonadotropin releasing hormone superagonist (GnRH agonist).
- BCC1023 Acetyl Angiotensinogen (1-14), porcine
- BCC6665 (±)-U-50488 hydrochloride
- BCC6015 (Z)-4-Hydroxytamoxifen 4-Hydroxytamoxifen is a selective estrogen receptor modulator (SERM).
- BCC4485 Medroxyprogesterone acetate Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors。
- BCC5121 XCT790 XCT-790 is a potent and selective inverse agonist for ERRα with an IC50 value of 0.37 μM. XCT-790 induces cell death in chemotherapeutic resistant cancer cells. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ.
- BCC6850 β-Funaltrexamine hydrochloride
- BCC7719 Estropipate Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis.
- BCC1740 Methylnaltrexone Bromide Methylnaltrexone (Bromide) is a peripheral-acting opioid receptor antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation.
- BCC1701 Leuprolide Acetate Leuprolide acetate (Leuprorelin acetate) is a potent gonadotropin-releasing hormone receptor agonist used for the treatment of prostate cancer, endometriosis, uterine fibroids.
- BCC5718 DSLET
- BCC5255 Oxymorphone
- BCC6979 TCPOBOP TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins.
- BCC5797 BAM 22P BAM-22P, a highly potent opioid peptide, is a potent opioid agonist.
- BCC6958 DAMGO DAMGO is a μ-opioid receptor (μ-OPR ) selective agonist with a Kd of 3.46 nM for native μ-OPR.
- BCC1671 JDTic 2HCl JDTic (dihydrochloride) is a potent antagonist of kappa-opioid receptors (KOR), blocking the κ-agonist U50, 488-induced antinociception.
- BCC1336 Alarelin Acetate Alarelin acetate is a synthetic GnRH agonist.
- BCC4506 AZD1981 AZD1981 is a potent and selective CRTh2 antagonist; displaces radio-labelled PGD2 from human recombinant DP2 with high potency (pIC50 = 8.4).
- BCC7596 Dynorphin A
- BCC7447 PHTPP PHTPP is a selective ERβ antagonist.
- BCC4488 Raloxifene HCl Raloxifene hydrochloride (LY156758 hydrochloride; LY139481 hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue.
- BCC5987 Dynorphin B Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.
- BCC5864 PL 017
- BCC5677 ICI 154,129
- BCC5875 Salvinorin A
- BCC4484 Hexestrol Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
- BCC7451 Y 134
- BCC4479 Altrenogest Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone.
- BCC1265 ADL5859 HCl ADL5859 is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel.
- BCC3910 TOK-001 Galeterone (TOK-001) is a multifunctional antiandrogen and CYP17 inhibitor (IC50=47 nM) in castration resistant prostate cancer (CRPC).
- BCC7082 FIT
- BCC1467 Cebranopadol Cebranopadol is an analgesic NOP and opioid receptor agonist with Kis/EC50s of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, 18 nM/110 nM for human NOP, MOP, KOP and delta-opioid peptide (DOP) receptor, respectively.
- BCC6838 BNTX maleate
- BCC5508 NVP-QAV680
- BCC6710 Naloxonazine dihydrochloride
- BCC6045 G-1 G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM.
- BCC5758 DPDPE
- BCC5675 ICI 174,864
- BCC3792 Imidapril HCl Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
- BCC2010 Toremifene Toremifene (NK 622; FC 1157a) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis.
- BCC4487 Toremifene Citrate Toremifene Citrate(NK 622; FC 1157a) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis.
- BCC2481 Bicalutamide Bicalutamide is a non-steroidal androgen receptor inhibitor.
- BCC7225 MPP dihydrochloride MPP dihydrochloride is a highly selective estrogen receptor alpha (ERα) antagonist. MPP dihydrochloride reduces the ratio of p-ERα/ERα.
- BCC1268 MDV3100 (Enzalutamide) Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an autophagy activator.
- BCC3724 ARN-509 Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.
- BCC4482 Estradiol valerate Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy drugs.
- BCC2491 Finasteride Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM).
- BCC6000 Fentanyl citrate