Home >> Research Area >> Membrane Transporter/Ion Channel >> Potassium Channel

Products for Potassium Channel

  1. Cat.No. Product Name Information
  2. BCC6904 1-EBIO 1-EBIO
  3. BCC7445 L-364,373 L-364,373
  4. BCC5005 Nateglinide Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. Nateglinide inhibits ATP-sensitive K+ channels in pancreatic β-cells. Nateglinide is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus[1][2]. Nateglinide
  5. BCC7231 Linopirdine dihydrochloride Linopirdine dihydrochloride
  6. BCC7182 E-4031 dihydrochloride E-4031 is a class III antiarrhythmic agent which selectively blocks hERG potassium channel. E-4031 dihydrochloride
  7. BCC3770 Dofetilide Dofetilide(Tikosyn) is a class III antiarrhythmic agent. Dofetilide
  8. BCC5006 ML133 HCl ML133 hydrochloride is a selective Kir2 family channels inhibitor, with an IC50 of 1.8 μM at pH 7.4 and 290 nM at pH 8.5. ML133 HCl
  9. BCC7232 XE 991 dihydrochloride XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 µM, 0.71 µM, 0.6 μM, and 0.98 µM, respectively. XE 991 dihydrochloride
  10. BCC7957 Penitrem A Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals. Penitrem A
  11. BCC7254 Y-27152 Y-27152, a prodrug of the KATP (Kir6) channel opener Y-26763, is a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. Y-27152
  12. BCC7253 Y-26763 Y-26763 is a K+ channel opener and active metabolite of Y-27152. Y-26763 is an ATP-sensitive K+ (KATP) channel activator. Y-26763
  13. BCC6932 Iberiotoxin Iberiotoxin
  14. BCC6126 VU 591 hydrochloride VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU 591 hydrochloride
  15. BCC6825 AM 92016 hydrochloride AM-92016 hydrochloride is a specific blocker of rectifier potassium current (IK). AM-92016 hydrochloride delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse thereby restricting the duration of the nerve impulse. AM 92016 hydrochloride
  16. BCC2504 Repaglinide Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus. Repaglinide
  17. BCC7784 UK 78282 hydrochloride UK 78282 hydrochloride
  18. BCC7976 ML 277 ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM. ML 277
  19. BCC4777 Dronedarone HCl Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents. Dronedarone HCl
  20. BCN2176 Dronedarone Dronedarone (SR 33589) is a newer therapeutic agent with a structural resemblance to amiodarone and a better side effect profile; it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF. Dronedarone
  21. BCC7710 Kaliotoxin Kaliotoxin
  22. BCC5000 Mitiglinide Calcium Mitiglinide Calcium (KAD-1229; S21403) is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. Mitiglinide Calcium
  23. BCC7709 Margatoxin Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research. Margatoxin
  24. BCC6831 ZM 226600 ZM 226600
  25. BCC5536 Azimilide Dihydrochloride Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. Azimilide Dihydrochloride
  26. BCC5535 Azimilide Azimilide
  27. BCC6427 Retigabine Retigabine
  28. BCC7779 NS 1619 NS-1619 is a selective large conductance Ca2+-activated K+-channel activator. NS 1619
  29. BCC7331 DMP 543 DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer. DMP 543
  30. BCC7055 Chromanol 293B Chromanol 293B
  31. BCC7080 (-)-[3R,4S]-Chromanol 293B (-)-[3R,4S]-Chromanol 293B
  32. BCC8026 Agitoxin 2 Agitoxin 2
  33. BCC7777 BL 1249 BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 μM and 8.0 μM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) than vascular tissue (EC50 of 21.0 μM). BL 1249
  34. BCC1809 NS309 NS309 is a positive modulator of small- and intermediate- conductance Ca2+-activated K+ channels (KCa2 and KCa3.1 channels); increases Ca2+ sensitivity. Displays no activity at BK channels. NS309
  35. BCC7984 MaxiPost Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo. MaxiPost
  36. BCC4377 Amiodarone HCl Amiodarone hydrochloride is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. Amiodarone HCl
  37. BCC7016 UCL 1684 UCL 1684
  38. BCC7671 Valinomycin Valinomycin (NSC 122023) is a cyclic depsipeptide antibiotic first isolated from Streptomyces fulvissimus, act as a potassium selective ionophore. Valinomycin (NSC 122023) inhibits lymphocyte proliferation by its effects on the cell membrane, and induces apoptosis in CHO cells. Valinomycin induces activation of PINK1 leading to Parkin Ser65 phosphorylation. Valinomycin
  39. BCC7448 BMS 191011 BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models. BMS 191011
  40. BCC5002 Gliclazide Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic. Gliclazide
  41. BCC5990 ShK-Dap22 ShK-Dap22
  42. BCC7141 Apamin Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca2+-activated K+ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity. Apamin
  43. BCC5740 Tertiapin-Q Tertiapin-Q
  44. BCC4788 Indapamide Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure. Indapamide
  45. BCC1122 TRAM-34 TRAM-34 is a highly selective blocker of intermediate-conductance calcium-activated K+ channel (IKCa1) (Kd=20 nM). TRAM-34
  46. BCC3785 Glipizide Glipizide(K 4024; CP 2872) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes. Glipizide
  47. BCC7803 VU 590 dihydrochloride VU 590 dihydrochloride
  48. BCC7499 PD 118057 PD-118057 is a human ether-a-go-go-related gene (hERG) channel activator that does not cause hERG blockade. PD 118057
  49. BCC6338 ICA 110381 ICA 110381 (Compound 16) is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy. ICA 110381 is a KCNQ2/Q3 agonist (EC50=0.38 μM) as well as KCNQ1 antagonist (IC50=15 μM). ICA 110381
  50. BCC5003 Gliquidone Gliquidone (AR-DF 26) is an anti-diabetic drug in the sulfonylurea class, used in the treatment of diabetes mellitus type 2. Gliquidone
  51. BCC6190 NS 3623 NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS 3623
  52. BCC6307 NS 6180 NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation. NS 6180
  53. BCC4297 Minoxidil Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM. Minoxidil
  54. BCC7743 SKA 31 SKA-31 is a potent potassium channel activator with EC50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1, KCa2.2, KCa2.1 and KCa2.3, respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure. SKA 31
  55. BCC7872 NS 5806 NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2. NS 5806
  56. BCC7398 DPO-1 DPO-1
  57. BCC7552 NS 1643 NS1643 is a partial agonist of human ether-a-go-go-related gene (hERG) K(+) channels with an EC50 of 10.5 μM. NS 1643
  58. BCC5632 Tolbutamide Sodium Tolbutamide Sodium
  59. BCC7048 CP 339818 hydrochloride CP 339818 hydrochloride
  60. BCC6213 ML 213 ML213 is a selective activator of Kv7.2 and Kv7.4 channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively. ML 213
  61. BCC5267 4-Aminopyridine 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane. 4-Aminopyridine
  62. BCC7554 Tetraethylammonium chloride Non-selective K<sup>+</sup> channel blocker Tetraethylammonium chloride
  63. BCC7262 PNU 37883 hydrochloride PNU 37883 hydrochloride
  64. BCC7911 ICA 069673 ICA-069673 is a KCNQ2/Q3 potassium channel activator with an IC50 of 0.69 μM. ICA 069673
  65. BCC7027 P1075 P-1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6), with an EC50 value of 45 nM for SUR2B-KIR6 channel activation. P-1075 also P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts. P1075
  66. BCC5001 Tolbutamide Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic drug. Tolbutamide
  67. BCC5004 Nicorandil Nicorandil (SG-75) is potassium channel activator. Nicorandil
  68. BCC7914 GW 542573X GW 542573X
  69. BCC7388 Nonactin Nonactin is a naturally occurring macrotetrolide antibiotic from Streptomyces griseus. Nonactin acts as an ionophore for monovalent cations, including K+, and NH4+. Nonactin is able to uncouple the oxidative phosphorylation of mitochondria. Nonactin selectively induces apoptosis in cell lines harboring active mutant β-catenin. Nonactin inhibits the surface expression of endogenous HSP60. Nonactin
  70. BCC7927 Psora 4 Potent K<sub>V</sub>1.3 channel blocker Psora 4
  71. BCC7526 CyPPA CyPPA
  72. BCC6044 RuBi-4AP RuBi-4AP
  73. BCC7806 JNJ 303 JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP). JNJ 303
  74. BCC5424 VU 0240551 VU 0240551 is a small molecule inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2-overexpressing cells). VU 0240551
  75. BCC6639 YS-035 hydrochloride YS-035 hydrochloride
  76. BCC7446 UCL 2077 UCL 2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker (IC50 = 500 nM in hippocampal neurons in culture), having minimal effects on Ca2+ channels, action potentials, input resistance and the medium after hyperpolarization. UCL 2077 is also a subtype-selective blocker of the epilepsy associated KCNQ channels. UCL 2077
  77. BCC7038 Cromakalim Cromakalim
  78. BCC7039 Levcromakalim Levcromakalim ((-)-Cromakalim) is an ATP-sensitive K+ channel (KATP) activator. Levcromakalim
  79. BCC8063 ML365 ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3) with IC50 of 4 nM(thallium influx fluorescent assay) and 16 nM(automated electrophysiology assay). ML365
  80. BCC6290 NS 11021 NS 11021 is a potent and specific Ca2-activated big-conductance K＋ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials. NS 11021
  81. BCC6933 Charybdotoxin Charybdotoxin

Items 1 to 80 of 80 total

BioCrick BioTech
88# Keyuan road,Hi-Tech Zone
Chengdu, Sichuan 610042, PRC
Email: info@biocrick.com
Tel:86-28-8543-3893
Follow us:

BioCrick is one of the biggest natural products manufacturers in Asia

Our products can be used as reference standards,inhibitors in pharmacological research

Our MISSION is to provide Best-in-class High-purity natural compounds to researchers all around the world

© 2007-2026 BioCrick BioTech. All rights reserved.  sitemap

Menu Close
Search Now