others
Products for others
- Reagents(34)
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- Others(296)
- ASK1(1)
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- Actin(9)
- Free Fatty Acid Receptors(6)
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- ES-FLI1/RHA(1)
- Heme oxygenase(7)
- Retinoic Acid Receptors(16)
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- Myosin(6)
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- Cat.No. Product Name Information
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BCC4259
Ezatiostat hydrochloride
Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment.
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BCC7944
NCX 4040
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BCC7502
IBMX
IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively.
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BCC1456
CB 300919
CB 300919 is a quinazoline-based antitumour agent with high activity in the CH1 human ovarian tumour xenograft. CB 300919 has a continuous exposure (96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft.
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BCC3899
L-Kynurenine
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
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BCC1178
T0901317
T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively[1,2]. T0901317 induces its anti-proliferative and cytotoxic effects via an LXR-independent mechanism. T0901317 significantly suppresses cell proliferation and induces programmed cell death in a dose- and time-dependent manner. T0901317 can protect mice from high fat diet-induced obesity and insulin resistance.
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BCC6713
7-Nitroindazole
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BCC8031
MTT
MTT, a yellow tetrazole, is reduced to purple formazan in living cells, and used for assessing cell metabolic activity.
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BCC5849
Eledoisin-Related Peptide
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BCC6638
Ro 20-1724
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BCC8003
NKY 80
NKY80 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues.
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BCC6250
4-CMTB
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BCC3896
CH 223191
CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR). CH-223191 inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and inhibits TCDD-induced luciferase activity with an IC50 of 0.03 μM.
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BCC7962
Ro 5-3335
Ro5-3335, a benzodiazepine, acts as an inhibitor of core binding factor (CBF) leukemia. Ro5-3335 is a RUNX1-CBFβ interaction inhibitor that represses RUNX1/CBFB-dependent transactivation.
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BCN2185
Retinoic acid
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.
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BCC1984
Tanaproget
Tanaproget (NSP-989) is a novel nonsteroidal progesterone receptor agonist which can bind to the PR from various species with a higher relative affinity than reference steroidal progestins.
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BCC7609
AGK 2
AGK2 is a selective SIRT2 inhibitor with IC50 of 3.5 μM. AGK2 can also inhibit SIRT1 and SIRT3 with IC50 of 30 and 91 μM, respectively.
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BCC5351
Chlorambucil
Chlorambucil is an alkylating agent with antitumor activity.
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BCC1563
Etofenamate
Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain.
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BCC7555
Acephate
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BCC6209
STF 083010
STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress.
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BCC6262
KL 001
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BCC6261
RFRP 3 (human)
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BCC6840
SYM 2081
SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively.
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BCC6236
LDN-27219
LDN-27219 is a potent inhibitor of hTGase(Tissue transglutaminase) with an IC50 of 0.6 uM.
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BCC6040
INH1
INH1 is a small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal.
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BCC6506
BPTES
BPTES is an allosteric and selective glutaminase inhibitor with an IC50 of 0.16 μM.
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BCC4167
Sunifiram
Sunifiram (DM-235) is a piperazine derived ampakine-like drug which has nootropic effects in animal studies with significantly higher potency than piracetam.
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BCC3720
Allopurinol
Allopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
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BCC5111
PTC-209
PTC-209 is a specific BMI-1 inhibitor with an IC50 of 0.5 μM.
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BCC5337
4EGI-1
4EGI-1 is an inhibitor of eIF4E/eIF4G interaction, with a Kd of 25 μM against eIF4E binding.
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BCC1703
Levomefolic acid
Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
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BCC5803
T 0156 hydrochloride
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BCC7792
1-Oleoyl lysophosphatidic acid sodium salt
LPA1 and LPA2 agonist; inhibits differentiation of neural stem cells into neurons
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BCC7730
BPIPP
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BCC6186
Ceranib 1
Ceranib1 is a ceramidase inhibitor. Ceranib1 inhibits ceramidase activity toward an exogenous ceramide analog, induces the accumulation of multiple ceramide species, decreases levels of sphingosine and S1P. Ceranib1 inhibits the proliferation of ovarian cancer cells.
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BCC3901
Phortress
Prodrug of the antitumor agent 5F 203
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BCC5338
4E1RCat
4E1RCat is an inhibitor of cap-dependent translation, and inhibits eIF4E:eIF4GI interaction, with an IC50 an of ∼4 μM.
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BCC7498
FPR A14
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BCC1484
Cinaciguat
Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure.
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BCC7787
KH 7
KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays. KH7 is also a cAMP inhibitor.
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BCC7696
LG 101506
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BCC7684
DMPO
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BCC5544
DZ2002
DZ2002 is a potent and reversible S-Adenosyl-L-homocysteine Hydrolase(SAHH; AdoHcy Hydrolase) inhibitor with Ki of 17.9 nM.
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BCC7871
Gisadenafil besylate
Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 3.6 nM and prevents degradation of cyclic guanosine monophosphate (cGMP).
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BCC6957
Substance P
Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
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BCC7952
Auranofin
Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM.
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BCC6162
SMIFH2
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BCC5714
Saralasin
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BCC6717
17-ODYA
Alkynyl Stearic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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BCC7782
MM 11253
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BCC6066
ITX3
ITX3 is a specific and nontoxic inhibitor of the TrioN (N-terminal GEF domain of the multidomain Trio protein) with IC50 of 76 uM; inhibits TrioN-stimulated RhoG exchange in vitro.
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BCC7586
DL-Dithiothreitol
Dithiothreitol (DTT) is the common name for a small-molecule redox reagent known as Cleland's reagent; as a reducing or "deprotecting" agent for thiolated DNA.
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BCC1742
Metiamide
Metiamide (SK&F 92058) is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide.
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BCC8045
GSK 137647
GSK137647A is a selective FFA4 agonist, with pEC50 of 6.3, 6.2, and 6.1 for human, Mouse and Rat FFA4, respectively.
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BCC5323
Ipriflavone (Osteofix)
Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption.
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BCC5403
HLM006474
HLM006474 is a pan E2F inhibitor, which inhibits E2F4 DNA-binding with an IC50 of 29.8 µM in A375 cells.
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BCC1515
Darapladib
Darapladib is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with IC50 of 0.25 nM.
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BCC6063
CP 20961
CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis.
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BCC6516
Sodium Tauroursodeoxycholate (TUDC)
Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
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BCC6648
Etazolate hydrochloride
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BCC4244
NVP 231
NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage.
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BCC5543
YL-109
YL-109 is a novel anticancer agent which has ability to inhibit breast cancer cell growth and invasiveness in vitro and in vivo.
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BCC4170
Meclofenoxate hydrochloride
Meclofenoxate hydrochloride, an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.
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BCC6304
Carbetocin
Carbetocin (Lonactene; Duratocin) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth; an agonist at peripheral oxytocin receptors.
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BCC7415
Kisspeptin 10 (human)
Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression.
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BCC5761
Metastin (human)
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BCC5866
187-1, N-WASP inhibitor
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BCC3735
Bephenium Hydroxynaphthoate
Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.
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BCC4861
Sulindac
Sulindac (MK-231) is a non-steroidal antiinflammatory agent, acts as a COX-2 inhibitor, and inhibits overexpression of COX-2.
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BCC4061
Adrenosterone
Adrenosterone is a steroid hormone with weak androgenic effect.
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BCC1597
Glucose-conjugated MGMT inhibitor
O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
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BCC5556
Chloroprocaine HCl
Chloroprocaine HCl is a local anesthetic during surgical procedures.
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BCN5924
Triptonide
Triptonide(NSC 165677; PG 492), extracted from Tripterygium wilfordii Hook, inhibited the proliferation of mouse splenocytes induced by suboptimal concentration of concanavalin A or lipopolysaccharide at concentrations of 0.02, 0.1, and 0.5 mg/ml.
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BCC6347
CK 869
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM.
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BCC5420
α-Tocopherol phosphate
α-Tocopherol phosphate is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources.
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BCC7712
Z-Guggulsterone
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
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BCC6439
Tiplaxtinin(PAI-039)
Tiplaxtinin is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 μM.
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BCC5434
2'-Deoxycytidine hydrochloride
2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
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BCC7066
MDL 12330A hydrochloride
Cyclic nucleotide PDE inhibitor; also adenylyl cyclase inhibitor
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BCC4843
Salubrinal
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM in a cell-free assay.
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BCC7571
Cyclapolin 9
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BCC1612
GW3965
GW3965 is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively.
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BCC3790
GW3965 HCl
GW3965 hydrochloride is a potent and selective liver X receptor (LXR) agonist with EC50s of 190 and 30 nM for hLXRα and hLXRβ , respectively.
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BCC4185
Palovarotene
Palovarotene is a nuclear retinoic acid receptor γ (RAR-γ) agonist.
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BCC6829
ODQ
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BCC3713
5-Chloro-1,10-phenanthroline
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BCC5397
Antitumor Compound 1
Antitumor agent-3 is a potent compound which comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.
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BCC6311
H2L 5765834
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BCC6837
S-Isopropylisothiourea hydrobromide
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BCC6298
Skp2 Inhibitor C1
Skp2 Inhibitor C1(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation, selectively inhibited Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts.
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BCC3805
Lithocholic Acid
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.
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BCC6088
CK 666
CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation.
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BCC6677
EBPC
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BCC3902
ITE
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM. ITE also has immunosuppressive activity.
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BCC7683
FAK Inhibitor 14
Y15 is a potent and specific inhibitor of focal adhesion kinase (FAK) that inhibits its autophosphorylation activity, decreases the viability of cancer cells, and blocks tumor growth.
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BCC8005
PA 452
PA452, retinoic X receptor (RXR) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development.
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BCC5572
Obeticholic Acid
Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy.
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BCC1684
Ko 143
Ko 143 is a potent and selective ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor. Ko 143 displays >200-fold selectivity over P-gp and MRP-1 transporters.
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BCC6670
Diphenyleneiodonium chloride
Diphenyleneiodonium chloride is a NADPH oxidase (NOX) inhibitor and also functions as a TRPA1 activator with an EC50 of 1 to 3 μM. Diphenyleneiodonium chloride selectively inhibits intracellular reactive oxygen species.