HDAC
Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.
Products for HDAC
- Cat.No. Product Name Information
- BCC1476 CHAPSZwitterionic detergent for membrane proteins,nondenaturing
- BCC1514 DaminozideSelective KDM2/7 inhibitor
- BCC1888 Resminostat hydrochlorideHDAC inhibitor
- BCC1893 RG2833Brain-penetrant HDAC inhibitor
- BCC1987 TasquinimodAntiangiogenic and antineoplastic agent
- BCC2144 Rocilinostat (ACY-1215)Selective HDAC6 inhibitor
- BCC2145 Vorinostat (SAHA, MK0683)Class I and II HDAC inhibitor
- BCC2146 Mocetinostat (MGCD0103, MG0103)HDAC inhibitor,isotype-selective and potent
- BCC2147 JNJ-26481585Potent HDAC inhibitor
- BCC2148 PCI-34051Potent and selective HDAC8 inhibitor
- BCC2149 CUDC-101Multitargeted HDAC inhibitor
- BCC2150 ITF2357 (Givinostat)HDAC inhibitor
- BCC2151 MC1568Selective HDAC class II (IIa) inhibitor
- BCC2152 Pracinostat (SB939)Pan-HDAC inhibitor
- BCC2153 Belinostat (PXD101)Hydroxamate-type HDAC inhibitor
- BCC2155 PCI-24781 (CRA-024781)Pan-HDAC inhibitor
- BCC2156 Valproic acid sodium salt (Sodium valproate)Histone deacetylase inhibitor; enables induction of pluripotent stem cells from somatic cells
- BCC2157 DroxinostatSelective HDAC inhibitor
- BCC2158 Tubastatin AHDAC6 inhibitor,potent and selective
- BCC2159 CI994 (Tacedinaline)HDAC inhibitor
- BCC2160 LAQ824 (NVP-LAQ824,Dacinostat)HDAC inhibitor,potent and novel
- BCC2161 AR-42 (OSU-HDAC42)HDAC inhibitor,novel and potent
- BCC2162 M344Histone deacetylase inhibitor
- BCC2163 ScriptaidHistone deacetylase inhibitor
- BCC2164 Sodium PhenylbutyrateHistone deacetylase inhibitor
- BCC2165 Resminostat (RAS2410)Potent HDAC inhibitor
- BCC2420 KD 5170HDAC inhibitor
- BCC2421 LMK 235Selective HDAC4/HDAC5 inhibitor
- BCC2422 NCH 51Histone deacetylase inhibitor
- BCC2423 NSC 3852Histone deacetylase inhibitor
- BCC2424 PyroxamideHistone deacetylase inhibitor
- BCC2425 SBHAHistone deacetylase inhibitor
- BCC2426 TC-H 106Class I histone deacetylase inhibitor
- BCC2427 TCS HDAC6 20bSelective HDAC6 inhibitor
- BCC2428 TubacinHDAC6 inhibitor,potent,selective,reversible,cell-permeable
- BCC3595 Entinostat (MS-275,SNDX-275)HDAC1 and HDAC3 inhibitor
- BCC3597 Romidepsin (FK228, depsipeptide)Potent and selective class I histone deacetylase inhibitor; antitumor
- BCC3599 ApicidinPotent histone deacetylase inhibitor
- BCC3601 Panobinostat (LBH589)HDAC inhibitor
- BCC3605 Trichostatin A (TSA)Potent histone deacetylase inhibitor; induces accelerated dedifferentiation of primordial germ cells
- BCC3877 Tubastatin A HClHDAC6 inhibitor,potent and selective
- BCC3991 RGFP966Specific HDAC3 inhibitor
- BCC3993 TMP269HDAC 4/5/7/9 inhibitor
- BCC4260 Valproic acidHDAC1 inhibitor
- BCC5488 Santacruzamate A (CAY10683)HDAC inhibitor, potent and selective
- BCC5542 CAY10603
- BCC5652 BRD73954