HDAC

Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.

Products for HDAC

  1. Cat.No. Product Name Information
  2. BCC1476 CHAPSZwitterionic detergent for membrane proteins,nondenaturing
  3. BCC1514 DaminozideSelective KDM2/7 inhibitor
  4. BCC1888 Resminostat hydrochlorideHDAC inhibitor
  5. BCC1893 RG2833Brain-penetrant HDAC inhibitor
  6. BCC1987 TasquinimodAntiangiogenic and antineoplastic agent
  7. BCC2144 Rocilinostat (ACY-1215)Selective HDAC6 inhibitor
  8. BCC2145 Vorinostat (SAHA, MK0683)Class I and II HDAC inhibitor
  9. BCC2146 Mocetinostat (MGCD0103, MG0103)HDAC inhibitor,isotype-selective and potent
  10. BCC2147 JNJ-26481585Potent HDAC inhibitor
  11. BCC2148 PCI-34051Potent and selective HDAC8 inhibitor
  12. BCC2149 CUDC-101Multitargeted HDAC inhibitor
  13. BCC2150 ITF2357 (Givinostat)HDAC inhibitor
  14. BCC2151 MC1568Selective HDAC class II (IIa) inhibitor
  15. BCC2152 Pracinostat (SB939)Pan-HDAC inhibitor
  16. BCC2153 Belinostat (PXD101)Hydroxamate-type HDAC inhibitor
  17. BCC2155 PCI-24781 (CRA-024781)Pan-HDAC inhibitor
  18. BCC2156 Valproic acid sodium salt (Sodium valproate)Histone deacetylase inhibitor; enables induction of pluripotent stem cells from somatic cells
  19. BCC2157 DroxinostatSelective HDAC inhibitor
  20. BCC2158 Tubastatin AHDAC6 inhibitor,potent and selective
  21. BCC2159 CI994 (Tacedinaline)HDAC inhibitor
  22. BCC2160 LAQ824 (NVP-LAQ824,Dacinostat)HDAC inhibitor,potent and novel
  23. BCC2161 AR-42 (OSU-HDAC42)HDAC inhibitor,novel and potent
  24. BCC2162 M344Histone deacetylase inhibitor
  25. BCC2163 ScriptaidHistone deacetylase inhibitor
  26. BCC2164 Sodium PhenylbutyrateHistone deacetylase inhibitor
  27. BCC2165 Resminostat (RAS2410)Potent HDAC inhibitor
  28. BCC2420 KD 5170HDAC inhibitor
  29. BCC2421 LMK 235Selective HDAC4/HDAC5 inhibitor
  30. BCC2422 NCH 51Histone deacetylase inhibitor
  31. BCC2423 NSC 3852Histone deacetylase inhibitor
  32. BCC2424 PyroxamideHistone deacetylase inhibitor
  33. BCC2425 SBHAHistone deacetylase inhibitor
  34. BCC2426 TC-H 106Class I histone deacetylase inhibitor
  35. BCC2427 TCS HDAC6 20bSelective HDAC6 inhibitor
  36. BCC2428 TubacinHDAC6 inhibitor,potent,selective,reversible,cell-permeable
  37. BCC3595 Entinostat (MS-275,SNDX-275)HDAC1 and HDAC3 inhibitor
  38. BCC3597 Romidepsin (FK228, depsipeptide)Potent and selective class I histone deacetylase inhibitor; antitumor
  39. BCC3599 ApicidinPotent histone deacetylase inhibitor
  40. BCC3601 Panobinostat (LBH589)HDAC inhibitor
  41. BCC3605 Trichostatin A (TSA)Potent histone deacetylase inhibitor; induces accelerated dedifferentiation of primordial germ cells
  42. BCC3877 Tubastatin A HClHDAC6 inhibitor,potent and selective
  43. BCC3991 RGFP966Specific HDAC3 inhibitor
  44. BCC3993 TMP269HDAC 4/5/7/9 inhibitor
  45. BCC4260 Valproic acidHDAC1 inhibitor
  46. BCC5488 Santacruzamate A (CAY10683)HDAC inhibitor, potent and selective
  47. BCC5542 CAY10603
  48. BCC5652 BRD73954

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