Intracellular Signaling
Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis. Errors in signaling interactions and cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated more effectively and, theoretically, artificial tissues may be created.
Intracellular Signaling Products Targets
- Cdc25 Phosphatase (2)
- STAT (10)
- PI 3-kinase (22)
- JAK (10)
- PFKFB3 (3)
- Hexokinases (1)
- Protein Kinase G (3)
- NFKB and IKB (30)
- Others (3)
- Cyclooxygenase (24)
- IRAK (1)
- PORCN (4)
- beta-catenin (13)
- PPARγ (16)
- PPARδ (5)
- PPARα (7)
- Inositol Phosphatase (3)
- MYC (1)
- Sphingosine Kinase (2)
- RSK (4)
- Protein Kinase D (3)
- Polo-like Kinase (5)
- Pim Kinase (4)
- PERK (2)
- Phosphoinositide-dependent Kinase 1 (5)
- P21-activated Kinases (2)
- Myosin Light Chain Kinase (4)
- mTOR (14)
- Monopolar Spindle 1 Kinase (2)
- Mnk (2)
- MK2 (2)
- MEK (9)
- LIMK (3)
- Focal Adhesion Kinase (4)
- DNA-Dependent Protein Kinase (6)
- Diacylglycerol Kinase (2)
- Death-Associated Protein Kinase (1)
- Checkpoint Kinase (3)
- Casein Kinase 2 (3)
- Casein Kinase 1 (7)
- Bruton's Tyrosine Kinase (3)
- ATM and ATR Kinase (3)
- Akt (Protein Kinase B) (11)
- Adeonsine Kinase (2)
- Abl Kinase (9)
- Hsp90 (10)
- Hsp70 (4)
- Protein Kinase A (9)
- Protein Kinase C (29)
- Calmodulin-Dependent Kinase (8)
- LRRK2 (4)
- ERK (6)
- DYRK (3)
- Estrogen and Related Receptor (33)
- Tankyrase (5)
- ITK (2)
- ASK1 (2)
- Syk Kinase (4)
- Src Kinase (21)
- Raf Kinase (7)
- IαB Kinase (6)
- p38 MAPK (16)
- Janus N-terminal Kinase (12)
- Androgen Receptor (11)
- Glycogen Synthase Kinase 3 (20)
- AMPK (7)
- Rho-Kinases (9)
- AP-1 (2)
- SREBP (2)
- NUAK (2)
- Telomerase (3)
- Retinoid X Receptor (13)
- Retinoic Acid Receptor (22)
- Proteasome (5)
- Phospholipase (16)
- Lipase (4)
- G Protein (Small) (23)
- Hedgehog Signaling (15)
- DNA Topoisomerase (12)
- DNA, RNA and Protein Synthesis (46)
- Protein Tyrosine Phosphatases (5)
- Protein serine and threonine phosphatase (16)
- Histone Deacetylase (19)
- Aurora Kinase (9)
- Cyclin-Dependent Protein Kinase (21)
Products for Intracellular Signaling - Page 62
- Cat.No. Product Name Information/Activity
-
BCC6166
SR 1664
1338259-05-4
-
BCC6199
Cardionogen 1
577696-37-8
-
BCC6258
CCT 031374 hydrobromide
1219184-91-4
-
BCC3632
ICG 001
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
-
BCC5401
iCRT 14
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase.
-
BCC5602
IWP 4
IWP-4 is a small molecule Wnt inhibitor with an IC50 of 25 nM.
-
BCC5102
IWR-1-endo
IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.
-
BCC7823
exo-IWR 1
1127442-87-8
-
BCC6251
JW 67
442644-28-2
-
BCC7704
PNU 74654
PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell.


