microbiology and virology

Cat.No. Product Name Information

BCC1108 Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.

BCC3780 Flucytosine Flucytosine (5-Fluorocytosine, 5-FC, Ancobon), a fluorinated pyrimidine analogue, is an antifungal drug.

BCC5414 Helioxanthin derivative 5-4-2 Helioxanthin derivative 5-4-2 is an analogue of helioxanthin, exhibites significant in vitro anti-HBV activity with EC50 of 0.08 uM in HepG2.2.15 cells.

BCC4690 Oseltamivir phosphate Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

BCC4261 Tenofovir hydrate Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

BCC1109 Entecavir Hydrate Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.

BCC5467 Flumorph Flumorph(SYP-L190) is a carboxylic acid amide (CAA) fungicide.

BCC2019 Tulathromycin A Tulathromycin A is a macrolide antibiotic.

BCC4849 SRPIN340 SRPIN340 is an ATP-competitive serine-arginine-rich protein kinase (SRPK) inhibitor, with a Ki of 0.89 μM for SRPK1.

BCC4837 Retapamulin Retapamulin(SB-275833) is a topical antibiotic, which binds to both E.

BCC4137 TAK-779 TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells. TAK-779

BCC4096 Cephalexin monohydrate Cefalexin monohydrate is a cephalosporin antibiotic.

BCC5083 Daunorubicin HCl Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) is a topoisomerase II inhibitor with potent antineoplastic activities. Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) inhibites DNA and RNA synthesis in sensitive and resistant Ehrlich ascites tumor cells. Daunorubicin HCl

BCC3755 Clotrimazole Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

BCC5515 Isavuconazole Isavuconazole (BAL-4815) is a triazole prodrug with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.

BCC3882 Dapivirine (TMC120) Dapivirine(TMC 120, TMC 120 R147681) is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates.

BCC5311 Bruceine A

BCC4130 T 705 Favipiravir (T-705) is a novel viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with IC50 of 341 nM. T 705

BCC5027 Etravirine (TMC125) Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

BCC5404 Tyrphostin A1 Tyrphostin A1(AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.

BCC5202 Y-320 Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Y-320

BCC5028 Stavudine (d4T) Stavudine is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

BCC4225 Gatifloxacin mesylate Gatifloxacin mesylate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin mesylate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin mesylate can be used to treat bacterial conjunctivitis in vivo.

BCC5478 Tildipirosin Tildipirosin, a long-acting macrolide, has antibiotic activity.

BCC1846 Peramivir Peramivir (RWJ-270201;BCX-1812) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging form 0.9 to 4.3 nM for nine NA subtypes.

BCC1637 I2906 I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis. I2906

BCC1791 NBD-557 NBD-557 is a potentially HIV-1 inhibitor. NBD-557

BCC1790 NBD-556 NBD-556 is small molecule mimetic of CD4, NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. NBD-556

BCC1811 Nucleozin Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.

BCC3862 Telbivudine Telbivudine, a specific inhibitor of hepatitis B virus (HBV) replication, is an antiviral drug used in the treatment of hepatitis B infection.

BCC1311 5-hydroxypyrazine-2-carboxylic acid 5-Hydroxypyrazine-2-Carboxylic Acid, a metabolite of anti-tuberculosis drug pyrazinamide (PZA).

BCC4050 BAY 57-1293 Pritelivir (BAY 57-1293; AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2. BAY 57-1293

BCC1669 JC-1 JC-1, a fluorescent lipophilic carbocyanine dye, that can be used to measure mitochondrial membrane potential. JC-1

BCC1523 Delafloxacin meglumine

BCC4505 BMS-378806 BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.

BCC1160 Doripenem Hydrate Doripenem monohydrate is a new member of the carbapenem class of beta-lactam antibiotics with broad-spectrum coverage of Gram-positive, Gram-negative and anaerobic pathogens.

BCC5206 Amikacin

BCC3675 Maraviroc Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.

BCC8066 Tenofovir alafenamide Tenofovir alafenamide (GS-7340) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.

BCC8067 Tenofovir Alafenamide Fumarate Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.

BCC6447 tenofovir diphosphate

BCC5266 Ceftaroline fosamil Ceftaroline fosamil (TAK-599) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

BCC4764 Besifloxacin HCl Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic.

BCC4106 CMX001 CMX001 (Brincidofovir; HDP-CDV) was developed as an orally active, lipophilic form of cidofovir (CDV); has enhanced activity in vitro and in vivo compared to CDV against certain herpesviruses, adenoviruses and orthopoxviruses. CMX001

BCC5192 Carbenicillin Carbenicillin is broad-spectrum semisynthetic penicillin derivative used parenterally.

BCC1698 Lersivirine Lersivirine(UK-453061) is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI, IC50=119 nM) with a unique resistance profile that exhibits potent antiretroviral activity against wild-type human immunodeficiency virus and clinically relevant NNRTI-resistant strains.

BCC1878 R-1479 R-1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM). R-1479

BCC1800 Nifuratel Nifuratel(NF 113, SAP 113) is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal (Trichomonas).

BCC1897 Rilpivirine Rilpivirine (R278474; TMC278) is a type of anti-HIV medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI).

BCC1962 SQ109 SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent. SQ109

BCC5194 Pentamidine dihydrochloride Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.

BCC6379 Carminomycin

BCC1737 Mefloquine hydrochloride Mefloquine hydrochloride is a quinoline antimalarial drug that is structurally related to the antiarrhythmic agent quinidine.

BCC3778 Ethionamide Ethionamide(2-ethylthioisonicotinamide) is an antibiotic used in the treatment of tuberculosis.

BCC2527 Cefaclor Cefaclor is an effective antibiotic agent, and specifically binds to penicillin-binding protein 3 (PBP 3).

BCC5286 Apilimod Apilimod is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively.

BCC4136 BMS-538203 BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent.

BCC3718 Albendazole Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.

BCC4829 Praziquantel Praziquantel is an anthelmintic effective against flatworms.

BCC4877 Vidarabine Vidarabine (Ara-A) an antiviral drug which is active against herpes simplex and varicella zoster viruses.

BCC1917 Salinomycin sodium salt Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt (Salinomycin sodium) acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. Salinomycin sodium salt (Salinomycin sodium) shows selective activity against human cancer stem cells.

BCC3825 Nitrofurazone Nitrofurazone (NFZ;Nitrofural) is a bactericidal compound used as an antibiotic most commonly in the form of ointments.

BCC4095 Cephalexin hydrochloride Cefalexin hydrochloride is a cephalosporin antibiotic.

BCC2038 Vicriviroc maleate Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC90s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570). Vicriviroc maleate

BCC3829 Olsalazine Sodium Olsalazine Disodium is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.

BCC8047 Toyocamycin Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM. Toyocamycin (Vengicide) induces apoptosis. Toyocamycin (Vengicide) shows no effect on IRE1α auto-phosphorylation.

BCC4937 Rifapentine Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.

BCC3748 Cefoperazone Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.

BCC4706 Primaquine Diphosphate Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gametocytocide in falciparum malaria.

BCC4858 Sulfanilamide Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.

BCC5303 Demeclocycline hydrochloride Demeclocycline hydrochloride is a tetracycline antibiotic; is an antibiotic in the treatment of Lyme disease, acne, and bronchitis.

BCC5253 Nimorazole Nimorazole (K-1900) is a nitroimidazole anti-infective.

BCC4855 Sulfameter Sulfameter(Bayrena) is a long-acting sulfonamide antibacterial.

BCC1382 Avermectin B1a Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.

BCC1383 Avermectin B1b

BCC3859 Sulfadiazine Sulfadiazine belongs to the class of sulfonamide antibiotics that are used for veterinary purposes worldwide, mainly in pig production. Sulfadiazine also used for toxoplasmosis.

BCC4230 Norfloxacin hydrochloride Norfloxacin hydrochloride is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

BCC4870 Toltrazuril Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.

BCC2008 Toltrazuril sulfone Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites.

BCC1574 Fiacitabine Fiacitabine(NSC 382097; FIAC; FOAC) is a selective inhibitior of DNA replication of herpes simplex virus(HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively.

BCC3763 Didanosine Didanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.

BCC4231 Pefloxacin Pefloxacin is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections.

BCC4821 Pefloxacin Mesylate Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections.

BCC4688 Norfloxacin Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

BCC4033 Tilbroquinol Tilbroquinol is an antiprotozoal agent effective against amoebiasis. It has also been used against Vibrio cholerae.

BCC1381 Avermectin B1 Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.

BCC5274 Ceftazidime Ceftazidime (GR20263) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases.

BCC4936 Rifabutin Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

BCC5212 Niclosamide monohydrate Niclosamide monohydrate is an inhibitor of STAT with IC₅₀ of 0.7 μM and inhibits DNA replication in a cell-free assay.

BCC5195 Ethambutol Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

BCC3775 Enoxacin (Penetrex) Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.

BCC5026 Zalcitabine Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection.

BCC6446 Solithromycin Solithromycin (CEM-101) is an orally bioavailable, effective antimicrobial agent, with IC50s for inhibition of cell viability, protein synthesis, and growth rate are 7.5 ng/mL, 40 ng/mL, and 125 ng/mL for Streptococcus pneumonia, Staphylococcus aureus, and Haemophilus influenzae, respectively. Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis.

BCC1392 Azathramycin Azathramycin (Azaerythromycin A) is an antibiotic.

BCN2216 Pimaricin Natamycin (pimaricin) is an antifungal macrolide polyene that binds to cell membrane sterols.

BCC2557 Aztreonam Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

BCC4889 Amorolfine HCl Amorolfine hydrochloride (Ro 14-4767/002) is a antifungal reagent.

BCC4819 Oxytetracycline (Terramycin) Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity. Oxytetracycline (Terramycin)

BCC5220 Dapsone Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Dapsone

BCC4916 Loteprednol etabonate Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology.

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