Intracellular Signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis. Errors in signaling interactions and cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated more effectively and, theoretically, artificial tissues may be created.

Intracellular Signaling Products Targets

Products for Intracellular Signaling - Page 13

  1. Cat.No. Product Name Information/Activity
  2. BCC6002 YM 511 148869-05-0 YM 511 chemical structure
  3. BCC7831 Zearalenone Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts. Zearalenone chemical structure
  4. BCC3940 AY 9944 dihydrochloride AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol. AY 9944 dihydrochloride chemical structure
  5. BCC3939 Ciliobrevin A Ciliobrevin A is a hedgehog (Hh) signaling pathway inhibitor with median inhibitory concentration (IC50) less than 10 μM. Ciliobrevin A chemical structure
  6. BCN2964 Cyclopamine Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine chemical structure
  7. BCC1587 GANT 58 GANT 58 is a potent Gli antagonist that inhibits GLI1-induced transcription with IC50 of 5 μM. GANT 58 chemical structure
  8. BCC1090 GANT61 GANT 61 is an inhibitor of Gli1 and Gli2 targeting the Hedgehog/GLI pathway. GANT61 chemical structure
  9. BCC3938 HPI 1 Inhibits Hedgehog signaling HPI 1 chemical structure
  10. BCC3936 JK 184 JK184 is a potent Hedgehog (Hh) pathway inhibitor with IC50 of 30 nM in mammalian cells. JK 184 chemical structure
  11. BCC7950 MRT 10 330829-30-6 MRT 10 chemical structure

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